Is Methionine Good for Health?

   Methionine (L-methionine) is a nutritional supplement and an essential amino acid in food.

Methionine is a sulfur-containing amino acid that can improve skin tone and elasticity, promote healthy hair, and promote nail growth. Methionine supplements are commonly used to treat infections. It is different from disease, but the scientific research supporting the improvement of the effectiveness of supplements for disease is limited. However, methionine is believed to be effective in treating Tylenol (acetaminophen) poisoning.

* Benefits of Methionine :

The sulfur in methionine provides many health benefits to the body. These may include:

-Nourish hair, skin and nails.

-Protect cells from pollutants.

-Promote the detoxification process.

-Slow down the aging process.

-Help absorb other nutrients (such as selenium and zinc).

-Support the excretion of heavy metals (such as lead and mercury) from the body.

Prevent the accumulation of too much fat in the liver (by acting as a fat promoter, a substance that promotes the breakdown of fats).

Reduce cholesterol levels by increasing the production of lecithin in the liver.

1. Tylenol (acetaminophen) poisoning treatment.

Methionine is used to treat Tylenol (acetaminophen) poisoning caused by other causes of overdose. Methionine is believed to prevent the by-product of acetaminophen from causing liver damage due to Tylenol overdose. However, other treatments can also be used, and methionine may not be the most effective.

2. Cancer.

Several studies have studied the ability of methionine to help cancer treatment, but the results of these studies are not consistent.

A 2013 meta-analysis of a scientific research report, “This meta-analysis shows that dietary methionine intake may be associated with reducing the risk of colorectal cancer, especially colon cancer. But it will take time to confirm these findings.”

Some research suggests that a low-methionine diet may be beneficial. There are certain types of cancer cells that depend on methionine for growth. Therefore, restricting the intake of foods containing methionine is beneficial to certain types of cancer patients because it can cause cancer cells to die.

3. Alzheimer’s disease.

Research on L-methionine and Alzheimer’s disease is only conducted in animal studies. In a 2015 rat model study, it was found that a diet rich in L-methionine can cause:

Amyloid (a substance that usually accumulates in the brains of people with Alzheimer’s disease) increases.

An increase in protein levels in the brain (increased causes proteins to aggregate and clump together to form an abnormal disease, found in Alzheimer’s disease patients).

Increased oxidative stress and inflammation (both of which increase the risk of Alzheimer’s disease).

-Memory loss and memory loss.

* Other uses.

Methionine is commonly used in other diseases, but there is a lack of clinical research results to support its safety and effectiveness in the following situations:

-Herpes simplex and herpes zoster (shingles)

-Menopausal symptoms

-Pancreatic inflammation

– Life issues



-Urinary Tract Infection (UTI)

-Asthma and allergies


* Possible side effects.

Methionine can cause some minor side effects, including nausea and vomiting, lethargy, and irritability. In fact, it is reported that nausea is a very common side effect that can be caused by methionine supplementation.

* Contraindications.

Contraindications are conditions or circumstances under which a particular technique or drug should not be used. Methionine is forbidden in the following situations:

-Liver damage.

-Hepatic encephalopathy (decreased brain function due to liver damage).

Severe liver disease (such as cirrhosis).

Acidosis (a state in which body acidity and blood acidity are too high).

Nutritional supplements are associated with an increased risk of heart disease.

Schizophrenia: Large doses of methionine (more than 20 grams per day for five days) are known to cause confusion, delirium, and agitation in patients with schizophrenia.

Methylenetetrahydrofolate reductase (MTHFR) deficiency (a genetic disorder related to abnormal management of heart disease risk).

* Dosage and method of use.

The recommended daily dose (RDA) for adult methionine (containing another amino acid called cysteine) is 14 mg/kg body weight per day.

Methionine is considered to be the most toxic among the nine amino acids in humans. Therefore, it is important to consult your doctor before taking methionine supplements. But a clinical study showed no signs of serious toxicity, except for very high doses of methionine. According to reports, a daily dose of 250 milligrams (mg) or about 25% of the recommended daily dose of methionine is safe.

The excess methionine dose for acetaminophen is 2.5 grams every four hours (maximum 10 grams). Because an overdose of Tylenol can be fatal, you should seek medical attention immediately instead of treating it yourself.

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